Oestrogel is a hormone replacement therapy (HRT) gel containing estradiol, a form of estrogen that is identical to the hormone naturally produced by the body. It is applied directly to the skin, where the estrogen is absorbed into the bloodstream to help relieve symptoms associated with menopause.

Oestrogel is commonly prescribed to treat menopausal symptoms such as hot flushes, night sweats, vaginal dryness, mood changes, and sleep disturbances caused by declining estrogen levels. It may also help protect against osteoporosis in postmenopausal women who are at increased risk of fractures and cannot use other osteoporosis treatments.

The gel is typically applied once daily to clean, dry, unbroken skin on the arms, shoulders, or thighs, following your healthcare provider's instructions. It should not be applied to the breasts, face, or genital area. Allow the gel to dry completely before dressing and avoid washing the application site for at least one hour after use.

As with all HRT medicines, Oestrogel should be used at the lowest effective dose for the shortest duration necessary. Women with an intact uterus are usually prescribed a progestogen alongside Oestrogel to reduce the risk of endometrial hyperplasia and cancer.

Always use Oestrogel exactly as prescribed and attend regular reviews with your healthcare provider to assess whether treatment remains appropriate.

Frequently asked questions
  • What is Oestrogel used for?

    Oestrogel is used to relieve symptoms of menopause caused by low estrogen levels, including hot flushes, night sweats, vaginal dryness, and sleep disturbances. It may also be prescribed to help prevent osteoporosis in certain postmenopausal women.

  • How do I apply Oestrogel?

    Apply the prescribed number of gel pumps once daily to clean, dry skin on the outer arms, shoulders, or thighs. Allow it to dry before dressing and avoid washing the area for at least one hour.

  • How long does Oestrogel take to work?

    Some women notice symptom improvement within a few weeks, although it may take up to three months to experience the full benefits. Your healthcare provider may adjust your dose if necessary.

  • Do I need progesterone with Oestrogel?

    If you still have your uterus, you will usually need to take a progestogen alongside Oestrogel. This helps protect the lining of the womb from excessive thickening caused by estrogen.

  • What are the possible side effects of Oestrogel?

    Common side effects may include breast tenderness, headaches, nausea, abdominal pain, skin irritation at the application site, or changes in menstrual bleeding. Seek medical advice if you experience unusual vaginal bleeding, chest pain, severe headaches, or signs of a blood clot.

  • Can I use Oestrogel during pregnancy?

    No. Oestrogel should not be used during pregnancy or while breastfeeding. If you become pregnant while using Oestrogel, stop treatment and contact your healthcare provider.

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