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- Naproxen Tablets
Naproxen Tablets contain naproxen, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation and help manage swelling associated with certain medical conditions.
Naproxen works by reducing the production of prostaglandins, substances involved in pain and inflammation. It may be prescribed for short-term painful conditions or as part of the management of longer-term inflammatory disorders.
Naproxen is used for a range of conditions, including:
- Period pain (dysmenorrhoea): Helps relieve menstrual cramps and associated discomfort.
- Back pain: May help manage pain associated with certain acute musculoskeletal conditions, such as strains and lower back pain.
- Joint and muscle pain: May be prescribed for inflammatory pain, sprains and strains.
- Osteoarthritis: Helps relieve pain and inflammation associated with degenerative joint disease.
- Rheumatoid arthritis: May help manage joint pain, swelling and stiffness as part of a wider treatment plan.
- Acute gout: May help reduce pain and inflammation during a gout attack.
- Ankylosing spondylitis: May help manage pain and stiffness associated with this inflammatory spinal condition.
Naproxen is not suitable for every type of pain, and treatment depends on the underlying cause, medical history and other medicines being taken.
Naproxen Tablets are available in 250mg and 500mg strengths, supplied in packs of 28 tablets.
A prescription is required for these products. Treatment is subject to a clinical assessment by an authorised prescriber, who will determine whether naproxen is appropriate and which strength, dose and duration should be used.
Active ingredient:
Naproxen.
- Naproxen 250mg Tablets contain 250mg of naproxen per tablet.
- Naproxen 500mg Tablets contain 500mg of naproxen per tablet.
Naproxen belongs to the NSAID group of medicines. It helps relieve pain and inflammation by inhibiting enzymes involved in prostaglandin production.
Other ingredients:
The inactive ingredients depend on the specific product formulation. Check the patient information leaflet supplied with your tablets, particularly if you have allergies or intolerances to ingredients such as lactose or tablet colourings.
The appropriate dosage of naproxen depends on the condition being treated, the strength prescribed and the patient's individual circumstances.
Naproxen 250mg Tablets
For period pain and certain acute musculoskeletal conditions, a commonly prescribed adult regimen is:
Take two tablets (500mg) initially, followed by one tablet (250mg) every 6–8 hours as required, according to the prescription instructions.
Different dosing schedules may be prescribed for conditions such as gout, osteoarthritis and rheumatoid arthritis.
Naproxen 500mg Tablets
For certain inflammatory conditions, including rheumatoid arthritis and osteoarthritis, a commonly prescribed adult regimen is:
Take one tablet (500mg) once or twice daily, according to the prescription instructions.
This regimen is not suitable for every condition. Acute gout and period pain may require different dosing schedules or tablet strengths.
How to Take Naproxen
- Take your tablets exactly as prescribed.
- Take naproxen with or after food to help reduce stomach irritation.
- Swallow tablets with water, following the instructions for your particular formulation.
- Use the lowest effective dose for the shortest necessary duration.
- Do not take more tablets or continue treatment for longer than prescribed.
- Do not combine naproxen with ibuprofen, diclofenac or other NSAIDs unless specifically instructed by a clinician.
- If you miss a dose, do not take a double dose to make up for it.
The instructions on your prescription label take priority over general dosage information on this page.
Common Side Effects
Possible side effects include:
- Indigestion or heartburn
- Stomach pain or discomfort
- Nausea or vomiting
- Diarrhoea or constipation
- Headache
- Dizziness
- Tiredness or drowsiness
- Skin rash
- Ringing in the ears
Taking naproxen with food may help reduce stomach irritation, but it does not eliminate the risk of ulcers or gastrointestinal bleeding.
Serious Side Effects
Stop taking naproxen and seek urgent medical advice if you experience:
- Black, tar-like stools or vomiting blood
- Severe or persistent stomach pain
- Unexplained bruising or bleeding
- Significant reduction in urination
- New or worsening swelling of the legs or ankles
- Yellowing of the skin or eyes
- A severe or widespread skin rash, particularly with blistering or peeling
Call 999 if you experience difficulty breathing, swelling of the face or throat, chest pain or symptoms of a stroke.
Serious side effects are more likely with higher doses, prolonged use or certain underlying medical conditions.
Storage Instructions
- Keep naproxen out of the sight and reach of children.
- Store according to the instructions on the original packaging and patient information leaflet.
- Keep tablets in their original packaging to protect them from environmental conditions.
- Do not use after the expiry date printed on the packaging.
- Do not use tablets if the packaging is damaged or the tablets appear altered.
- Return unwanted or expired medicines to a pharmacy for safe disposal.
Frequently asked questions
What is naproxen?
Naproxen is an NSAID used to relieve pain and inflammation associated with conditions such as period pain, arthritis, gout and certain musculoskeletal injuries.
Is naproxen a painkiller?
Yes. Naproxen relieves pain and also has anti-inflammatory properties.
Is naproxen an anti-inflammatory medicine?
Yes. It belongs to the non-steroidal anti-inflammatory drug group.
What conditions can naproxen treat?
Naproxen may be prescribed for period pain, acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gout, depending on clinical suitability.
Can naproxen be used for back pain?
Naproxen may be prescribed for certain types of back pain, particularly where inflammation or musculoskeletal injury is involved. New, severe or unexplained back pain requires appropriate assessment.
Can naproxen help with period pain?
Yes. Naproxen can help relieve menstrual cramps by reducing prostaglandin production.
Can naproxen treat gout?
Naproxen may be used to manage pain and inflammation during an acute gout attack. The dosing schedule for gout differs from some other conditions.
Is naproxen used for rheumatoid arthritis?
Yes. Naproxen may help manage pain, swelling and stiffness. It does not replace disease-modifying treatment for rheumatoid arthritis.
Can naproxen help with osteoarthritis?
Yes. It may help relieve osteoarthritis pain and inflammation, although the benefits and risks of ongoing treatment should be reviewed regularly.
Does naproxen cure arthritis?
No. Naproxen helps control symptoms but does not cure arthritis or prevent the progression of inflammatory joint disease.
How quickly does naproxen work?
Some people begin to notice pain relief within approximately one hour, although the onset and full benefit vary by formulation and condition. Anti-inflammatory benefits for some chronic conditions may take longer.
Can I take naproxen if I have asthma?
Some people with asthma experience serious reactions to NSAIDs. Tell your prescriber about asthma and any previous reactions to aspirin or ibuprofen.
Can naproxen affect fertility?
Naproxen may temporarily affect ovulation and make conception more difficult. Tell your prescriber if you are trying to become pregnant.


